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July 8, 2026PeerJOpen Access

Oropharyngeal dysphagia and gastroesophageal reflux disease in lung transplant patients: a systematic review and meta-analysis of incidence, risk factors, and clinical outcomes

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This review aims to synthesize evidence regarding the prevalence of oropharyngeal dysphagia and gastroesophageal reflux disease in lung transplant recipients and their associated risk factors and outcomes.
Systematic review and meta-analysis of studies from PubMed, Embase, Cochrane Library, and Web of Science until December 2025
Used a random-effects model to calculate prevalence rates and assess risk factors
Evaluated bias using the Newcastle–Ottawa Scale.
Oropharyngeal dysphagia had a pooled prevalence rate of 48% (95% CI [0.41–0.55]) among lung transplant patients
Gastroesophageal reflux disease had a pooled prevalence rate of 43% (95% CI [0.35–0.52])
Mechanical ventilation (OR = 5.37, 95% CI [3.25–8.86]) and reintubation (OR = 2.76, 95% CI [1.29–5.90]) were significant risk factors for OPD.

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Systematic review quantifies oropharyngeal dysphagia and GERD in lung transplant patients, highlighting clinical implications.

Tang et al. (2026) studied this question.

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