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July 8, 2026Journal of Functional BiomaterialsOpen Access

Balancing Osseointegration and Infection Control: The Role of Titanium Surface Topography in Peri-Implant Biology

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Authors

SISimina Angela Lăcrimioara IușanDFDana FeştilăIMIoana-Codruţa Mirică

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Overview

Randomized trial investigates titanium surface types for bacterial control and osteoblastic response in dental implants, suggesting improved outcomes with nanostructured surfaces.

Key Points

  • This study aims to understand how different titanium surface topographies impact bacterial colonisation and osteoblastic response in dental implants.
  • Titanium discs with distinct surface topographies were prepared and sterilised.
  • Co-cultures of mesenchymal stem cells with bacteria were established and examined.
  • Cell–bacteria interactions were analyzed using fluorescence microscopy and quantitative methods.
  • Nano surfaces exhibited the highest osteoblastic adhesion and viability, enhancing osseointegration.
  • Nano surfaces significantly reduced bacterial proliferation and biofilm formation compared to Ma and SLA surfaces.
  • Early cell attachment on Nano surfaces hindered subsequent bacterial adhesion, improving infection control.

Cite This Study

Iușan et al. (2026) studied this question.

synapsesocial.com/papers/6a4dea63d2ea289ef6284252https://doi.org/10.3390/jfb17070327
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