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January 1, 2015Journal of Periodontal & Implant ScienceOpen Access

Microgrooves on titanium surface affect peri-implant cell adhesion and soft tissue sealing; an in vitro and in vivo study

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Authors

HLHyo‐Jung LeeJLJaden S. LeeJLJung‐Tae Lee

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Overview

In vitro and in vivo study demonstrates enhanced cell adhesion and soft tissue sealing with titanium microgrooves.

Key Points

  • This research investigates how microgrooves on titanium surfaces affect the adhesion of peri-implant cells and the healing of soft tissues.
  • Three types of titanium discs were prepared: machined-surface, SLA-treated, and SLA with microgrooves.
  • Human gingival fibroblasts and murine osteoblastic cells were used for immunofluorescence assays on the discs.
  • Titanium implants with microgrooves were inserted into beagle dogs to observe tissue healing over 2 and 6 weeks.
  • Group C (microgrooved discs) showed the lowest water contact angle (62.89±5.66 θ) and highest surface energy (45±1.2 mN/m).
  • Significantly higher expression of adhesion molecules in hGFs and MC3T3-E1 cells was noted in group C.
  • Titanium implants with microgrooves exhibited strong adhesion to peri-implant soft tissue.

Cite This Study

Lee et al. (2015) studied this question.

synapsesocial.com/papers/6a5e249a69f6c368eabc4bachttps://doi.org/10.5051/jpis.2015.45.3.120
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Biologic width around titanium implants. A physiologically formed and stable dimension over time2000 · 310 citations
  2. 2Estimation of the surface free energy of polymers1969 · 9,487 citations
  3. 3Peri-implant Inflammation Defined by the Implant-Abutment Interface2006 · 478 citations
  4. 4Influence of Implant transmucosal design on early peri‐implant tissue responses in beagle dogs2013 · 21 citations