Key result
Isolated non-compaction of the left ventricular myocardium was associated with a similar rate of congestive heart failure compared to non-isolated cases (77.5% vs. 62.1%, P=0.322).
Why the study?
What is the frequency of cardiovascular complications in pediatric patients with isolated vs. non-isolated non-compaction of the left ventricular myocardium?
Population
66 pediatric patients with non-compaction of the left ventricular myocardium, including 25 with isolated…
Design
Cohort
Follow-up
median 12 months (range 0-51)
Authors
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Supports similar heart failure risk in isolated LV noncompaction; hypothesis-generating and requires validation in larger cohorts.
Cohort (n=66)
No
What is the frequency of cardiovascular complications in pediatric patients with isolated vs. non-isolated non-compaction of the left ventricular myocardium?
Absolute Event Rate: 77.5% vs 62.1%
p-value: p=0.322
In a pediatric population, non-compaction of the left ventricular myocardium is frequently associated with congestive heart failure, regardless of whether it is isolated or associated with other congenital heart defects.
Christian Lilje (2006) conducted a cohort in Non-compaction of the left ventricular myocardium (NCVM) (n=66). Isolated NCVM (i-NCVM) vs. Non-isolated NCVM (ni-NCVM) was evaluated on Congestive heart failure (CHF) at follow-up (p=0.322). Isolated non-compaction of the left ventricular myocardium was associated with a similar rate of congestive heart failure compared to non-isolated cases (77.5% vs. 62.1%, P=0.322).
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