Why the study?
This review summarises shifting paradigms in the treatment of ischemic left ventricular dysfunction, focusing on the REVIVED-BCIS2 trial results and its impact on key therapeutic goals.
Does percutaneous coronary intervention (PCI) improve survival, left ventricular function, arrhythmic risk, or quality of life compared to optimal medical therapy alone in patients with ischemic left ventricular dysfunction?
Does percutaneous coronary intervention (PCI) improve survival, left ventricular function, arrhythmic risk, or quality of life compared to optimal medical therapy alone in patients with ischemic left ventricular dysfunction?
Answers are grounded in this paper and cite their sources.
This review highlights that PCI offers no additional benefit over optimal medical therapy for survival or LV function in ischemic left ventricular dysfunction, challenging previous beliefs.
PURPOSE OF REVIEW: This review summarises the shifting paradigms in the treatment of ischemic left ventricular dysfunction, spotlighting the revascularization for ischemic ventricular dysfunction-British cardiovascular intervention society-2 (REVIVED-BCIS2) trial results and its impact on key therapeutic goals: survival, left ventricular function, arrhythmia prevention, quality of life and viability testing. RECENT FINDINGS: The REVIVED-BCIS2 trial, and its subsequent sub studies highlighted that (PCI) does not provide additional benefits to optimal medical therapy in terms of improving survival, left ventricular (LV) function, arrhythmic risk or quality of life. Additionally, viability testing did not differentiate patients who could benefit from PCI, although scar burden was found to be a significant predictor of outcome in these patients. SUMMARY: The outcomes of REVIVED have challenged multiple existing beliefs in the field of ischaemic left ventricular dysfunction management, emphasising the importance of investigating evidence free areas in our practice. Future work, including the STICH3 international consortium of trials, aims to answer some of the remaining unanswered questions.
No takes yet. Share an insight, caveat, or question.
Betemariam et al. (2024) conducted a review in ischemic left ventricular dysfunction. Percutaneous coronary intervention (PCI) vs. optimal medical therapy was evaluated on survival, left ventricular function, arrhythmic risk, or quality of life.
Synapse has enriched 10 related papers. Consider them for comparative context: