Key result
CABG improves long-term survival in extensive multivessel disease while PCI primarily enhances quality of life.
Why the study?
Ischemic cardiomyopathy is a leading cause of heart failure, but the optimal revascularization strategy for patients with reduced left ventricular function remains uncertain.
Does CABG or PCI improve survival or quality of life in patients with ischemic cardiomyopathy compared to optimal medical therapy?
Does CABG or PCI improve survival or quality of life in patients with ischemic cardiomyopathy compared to optimal medical therapy?
CABG improves long-term survival in ischemic cardiomyopathy with multivessel disease, while PCI offers symptom relief and quality of life improvements for high-risk patients ineligible for surgery.
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May guide CABG versus PCI decisions in multivessel disease; leaves open RCTs versus optimal medical therapy.
Prunea et al. (2025) conducted a review in Ischemic cardiomyopathy. CABG and PCI vs. Optimal medical therapy was evaluated. Coronary artery bypass grafting improves long-term survival in extensive multivessel disease, whereas percutaneous coronary intervention enhances quality of life without significant mortality benefit.
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