Key result
Tall stature (>183.0 cm) was associated with a significantly increased risk of incident heart failure (HR 2.04) compared to average height in older men, largely driven by incident atrial fibrillation.
Why the study?
Taller stature has been linked to increased atrial fibrillation risk, but the association between height and heart failure risk in older adults has not been well studied.
Is adult height associated with the incidence of atrial fibrillation and heart failure in older men?
Population
3346 men aged 60-79 years without HF, MI, or stroke at baseline
Comparison
5 height groups (<168.2, 168.2-172.5, 172.6-176.9, 177.0-183.0, and >183.0 cms)
Design
Prospective study
Follow-up
Mean period of 16 years
Authors
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Taller height was associated with higher AF and HF risk in older men; extends prior AF data but leaves causal role in HF open for prospective confirmation.
Cohort (n=3,346)
Yes
Is adult height associated with the incidence of atrial fibrillation and heart failure in older men?
Hazard Ratio: 2.04 (95% CI 1.23–3.39)
Absolute Event Rate: 8.8% vs 5.1%
Both short and tall stature are associated with an increased risk of heart failure in older men, with the risk in tall men largely driven by atrial fibrillation and QRS duration.
Wannamethee et al. (2021) conducted a cohort in Atrial fibrillation and heart failure (n=3,346). Tall stature (>183.0 cm) vs. Second height quartile (168.2-172.5 cm) was evaluated on Incident heart failure (HR 2.04, 95% CI 1.23, 3.39). Tall stature (>183.0 cm) was associated with a significantly increased risk of incident heart failure (HR 2.04) compared to average height in older men, largely driven by incident atrial fibrillation.
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