Key result
The tail-cuff technique significantly underestimates simultaneous core blood pressure changes during restraint compared to telemetry, though readings are similar to telemetry in undisturbed mice.
Population
C57Bl/6J mice implanted with radio-telemetry probes, including a model of hypertension induced by…
Comparison
Tail-cuff blood pressure measurement technique vs Radio-telemetry blood pressure measurement
Design
Preclinical
Authors
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Tail-cuff underestimates restraint-induced BP changes in mice; leaves open optimal noninvasive methods for reliable cardiovascular phenotyping.
Tail-cuff blood pressure measurement in mice underestimates simultaneous central blood pressure changes induced by restraint, but approximates baseline undisturbed telemetry readings.
Wilde et al. (2017) studied Blood pressure measurement. Tail-cuff technique vs. Telemetry was evaluated on Central blood pressure, heart rate, and temperature. The tail-cuff technique significantly underestimates simultaneous core blood pressure changes during restraint compared to telemetry, though readings are similar to telemetry in undisturbed mice.
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