Key result
Long-term maintenance of intraprocedural ablation endpoints, such as pulmonary vein disconnection (37.5% of PVs), was limited and did not differ significantly between patients with and without AF recurrence.
Why the study?
Does the long-term maintenance of intraprocedural ablation endpoints differ between patients with stable sinus rhythm and those with atrial fibrillation recurrence?
Observational (n=30)
Does the long-term maintenance of intraprocedural ablation endpoints differ between patients with stable sinus rhythm and those with atrial fibrillation recurrence?
p-value: p=not statistically significant
Common intraprocedural ablation endpoints such as PV disconnection and voltage abatement are poorly maintained long-term, even in patients who remain in stable sinus rhythm, suggesting permanent isolation may not be strictly required for clinical success.
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Limited AF ablation lesion durability in this cohort warrants caution; leaves open optimal strategies for durable isolation.
Pratola et al. (2007) conducted an observational in Drug-refractory persistent atrial fibrillation (n=30). Stable sinus rhythm post-ablation vs. Recurrence of atrial fibrillation was evaluated on Maintenance of intraprocedural end points (voltage abatement, PV disconnection, and exit block) (p=not statistically significant). Long-term maintenance of intraprocedural ablation endpoints, such as pulmonary vein disconnection (37.5% of PVs), was limited and did not differ significantly between patients with and without AF recurrence.
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