Key result
Pre-existing atrial fibrillation was associated with lower 12-month survival (74.9%) compared to sinus rhythm (83.5%, p<0.05) following MitraClip for mitral regurgitation.
Why the study?
Does baseline atrial fibrillation or heart rate affect the safety and efficacy of percutaneous mitral valve repair with MitraClip in patients with mitral regurgitation?
Population
760 patients undergoing percutaneous edge-to-edge mitral valve repair for mitral valve regurgitation (MR)
Comparison
Percutaneous edge-to-edge mitral valve repair… vs Patients with pre-existing sinus rhythm vs…
Design
Cohort
Follow-up
12 months
Authors
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AF associated with lower survival post-MitraClip; leaves open whether rhythm control improves outcomes in randomized trials.
Cohort (n=760)
Does baseline atrial fibrillation or heart rate affect the safety and efficacy of percutaneous mitral valve repair with MitraClip in patients with mitral regurgitation?
Absolute Event Rate: 74.9% vs 83.5%
p-value: p=<0.05
MitraClip can be performed safely and effectively regardless of baseline rhythm or heart rate, though patients with sinus rhythm exhibit higher 12-month survival than those with atrial fibrillation.
Jabs et al. (2017) conducted a cohort in Mitral valve regurgitation (n=760). Atrial fibrillation vs. Sinus rhythm was evaluated on 12-month survival (p=<0.05). Pre-existing atrial fibrillation was associated with lower 12-month survival (74.9%) compared to sinus rhythm (83.5%, p<0.05) following MitraClip for mitral regurgitation.
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