Key result
Prior AF linked to ~167% higher risk of death or HF rehospitalization after MitraClip.
Why the study?
There is uncertainty on the outlook of real-world patients with atrial fibrillation undergoing transcatheter mitral valve repair with MitraClip.
Does a history of atrial fibrillation increase the risk of adverse events in patients undergoing TMVR with MitraClip?
Population
116 patients undergoing TMVR at 3 tertiary care centers
Comparison
Patients with history of AF vs patients without AF
Design
Retrospective cohort study
Authors
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AF history may identify higher-risk MitraClip patients for closer surveillance; leaves open whether rhythm interventions improve outcomes.
Cohort (n=116)
Yes
Does a history of atrial fibrillation increase the risk of adverse events in patients undergoing TMVR with MitraClip?
Absolute Event Rate: 34.2% vs 12.8%
p-value: p=0.035
In patients undergoing TMVR with MitraClip, a history of atrial fibrillation is associated with a significantly higher risk of death or heart failure rehospitalization.
Arturo Giordano (2015) conducted a cohort in Significant mitral valve regurgitation (n=116). Atrial fibrillation vs. No atrial fibrillation was evaluated on Composite of death or rehospitalization for heart failure (p=0.035). In patients undergoing transcatheter mitral valve repair with MitraClip, a history of atrial fibrillation was associated with a significantly higher incidence of death or heart failure rehospitalization (34.2% vs 12.8%, p=0.035).
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