Key result
Abnormal myocardial perfusion and wall motion on cSE-WMP was associated with a 15.5% 5-year event rate of cardiac death or MI, compared to 5.9% for normal results, which was mitigated by revascularization.
Why the study?
Does coronary revascularization reduce cardiac death or nonfatal myocardial infarction in patients with abnormal stress myocardial contrast wall motion and perfusion imaging?
Population
1,329 patients with suspect or known coronary artery disease (CAD)
Comparison
Coronary revascularization after contrast… vs No revascularization after cSE-WMP
Design
Cohort
Follow-up
median 5.5 years
Authors
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Supports selective revascularization based on stress echo results in CAD; extends evidence for imaging-guided therapy.
Cohort (n=1,329)
Does coronary revascularization reduce cardiac death or nonfatal myocardial infarction in patients with abnormal stress myocardial contrast wall motion and perfusion imaging?
Absolute Event Rate: 15.5% vs 5.9%
p-value: p=0.001
Coronary revascularization following an abnormal stress myocardial contrast echocardiogram reduces the risk of cardiac events to a level comparable to patients with normal imaging.
Gaibazzi et al. (2017) conducted a cohort in Suspect or known coronary artery disease (n=1,329). Abnormal myocardial perfusion and wall motion on cSE-WMP vs. Normal myocardial perfusion and wall motion was evaluated on Cardiac death or nonfatal myocardial infarction (p=0.001). Abnormal myocardial perfusion and wall motion on cSE-WMP was associated with a 15.5% 5-year event rate of cardiac death or MI, compared to 5.9% for normal results, which was mitigated by revascularization.
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