Key result
Smoking one cigarette significantly reduced the breath-holding index in healthy young smokers immediately (p<0.0001) and up to 20 minutes after smoking compared to baseline.
Why the study?
Does smoking one cigarette reduce cerebrovascular reactivity in healthy young smokers?
Population
48 healthy young individuals (24 smokers and 24 controls matched for age and sex)
Comparison
Smoking one cigarette vs Healthy controls evaluated at corresponding time…
Design
Case-control
Follow-up
30 minutes
Authors
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Acute smoking may transiently impair cerebrovascular reactivity in young adults; hypothesis-generating and requires larger trials before clinical adoption.
Observational (n=48)
Does smoking one cigarette reduce cerebrovascular reactivity in healthy young smokers?
p-value: p=<0.0001
Smoking a single cigarette acutely impairs cerebrovascular reactivity, providing a potential hemodynamic mechanism for the increased risk of cerebrovascular disease in smokers.
Silvestrini et al. (1996) conducted an observational in Healthy (n=48). Smoking one cigarette vs. Healthy controls was evaluated on Breath-holding index (BHI) (p=<0.0001). Smoking one cigarette significantly reduced the breath-holding index in healthy young smokers immediately (p<0.0001) and up to 20 minutes after smoking compared to baseline.
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