Key result
Transcatheter mitral valve interventions, particularly edge-to-edge repair with the MitraClip system, offer a safe and effective treatment option for symptomatic severe mitral regurgitation in high-risk patients.
Transcatheter mitral valve interventions, particularly edge-to-edge repair, offer effective treatment options for high-risk or inoperable patients with severe mitral regurgitation.
Supports MitraClip consideration in high-risk severe MR; leaves open need for prospective data on durability and selection.
Transcatheter mitral valve intervention has emerged as an effective treatment option for symptomatic severe mitral regurgitation in patients considered to be inoperable or at high operative risk for surgical mitral valve surgery. Most transcatheter approaches are modifications of existing surgical approaches. Transcatheter edge-to-edge mitral valve repair with the MitraClip system has the largest clinical experience to date, as it offers a sustained clinical benefit in selected patients. This review aims to provide an up-to-date overview of transcatheter mitral valve interventions, including leaflet repair, annuloplasty, and mitral valve implantation.
No takes yet. Share an insight, caveat, or question.
Grasso et al. (2015) conducted a review in Severe Mitral Regurgitation. Transcatheter mitral valve interventions vs. Surgical mitral valve repair/replacement or medical management was evaluated. Transcatheter mitral valve interventions, particularly edge-to-edge repair with the MitraClip system, offer a safe and effective treatment option for symptomatic severe mitral regurgitation in high-risk patients.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: