What question did this study set out to answer?

The study aims to create a strategy for efficient three-dimensional volume acquisition of coronary arteries.

July 10, 2026Journal of the American College of Cardiology

Double-oblique free-breathing high resolution three-dimensional coronary magnetic resonance angiography

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Coronary artery disease (n=22). Intervention: Double-oblique free-breathing high resolution 3D coronary MRA vs. X-ray angiography. Primary outcome: Average length of contiguously visualized coronary arteries (p=NS).

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Key result

Double-oblique free-breathing 3D coronary MRA visualizes coronary anatomy similarly in healthy volunteers and patients.

P NS
n=22

Why the study?

Does double-oblique free-breathing high resolution 3D coronary MRA accurately depict extensive parts of native coronary arteries compared to X-ray angiography in patients with CAD?

Population

15 healthy adult volunteers and 7 patients with X-ray angiographically confirmed coronary artery disease

Comparison

Double-oblique free-breathing high resolution… vs X-ray angiography (in the patient cohort)

Design

Cross-sectional

Authors

MSMatthias StuberCardiac Imaging RBRené M. BotnarCardiac Imaging PDPeter G. DaniasTufts University

Discussion

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Implication

Double-oblique submillimeter free-breathing coronary MRA allows extensive visualization of native coronary arteries, showing good agreement with X-ray angiography in patients with CAD.

Key Points

The study aims to create a strategy for efficient three-dimensional volume acquisition of coronary arteries.
Fifteen healthy volunteers and seven patients with coronary artery disease underwent high-resolution 3D coronary magnetic resonance angiography.
Free-breathing navigator-gated techniques were utilized to improve volume acquisition efficiency.
Three-point planscan software was employed for accurate targeting of volumes.
The average length of the left main and left anterior descending arteries was 81.8 mm in healthy volunteers compared to 76.2 mm in patients (p = NS).
The right coronary artery showed lengths of 111.7 mm in volunteers and 79.3 mm in patients (p = NS).
There was good agreement between coronary MRA and X-ray angiography findings in patients.

Study Design

Type

Observational (n=22)

Structured PICO

Does double-oblique free-breathing high resolution 3D coronary MRA accurately depict extensive parts of native coronary arteries compared to X-ray angiography in patients with CAD?

Population

22 participants (15 healthy adult volunteers and 7 patients with confirmed coronary artery disease) undergoing free-breathing 3D coronary MRA.

Exposure

Double-oblique free-breathing high resolution three-dimensional coronary magnetic resonance angiography (MRA) using a three-point planscan software tool

Comparator

X-ray angiography (in the patient cohort)

Outcome

Length of contiguously visualized coronary arteries (left main, LAD, RCA) and agreement of anatomy and pathology with X-ray angiographysurrogate

Main Result

p-value: p=NS

Double-oblique submillimeter free-breathing coronary MRA allows extensive visualization of native coronary arteries, showing good agreement with X-ray angiography in patients with CAD.

Cite This Study

Stuber et al. (1999) conducted an observational in Coronary artery disease (n=22). Double-oblique free-breathing high resolution 3D coronary MRA vs. X-ray angiography was evaluated on Average length of contiguously visualized coronary arteries (p=NS). Double-oblique free-breathing 3D coronary MRA visualized an average left main and anterior descending artery length of 81.8 mm in healthy volunteers and 76.2 mm in patients (p=NS).

synapsesocial.com/papers/6a5064a2330ff8da2846ea37 https://doi.org/10.1016/s0735-1097(99)00223-5

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Implication

Double-oblique submillimeter free-breathing coronary MRA allows extensive visualization of native coronary arteries, showing good agreement with X-ray angiography in patients with CAD.

Double-oblique free-breathing high resolution three-dimensional coronary magnetic resonance angiography

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Double-oblique free-breathing high resolution three-dimensional coronary magnetic resonance angiography

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Also Consider