Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 10, 2026Scientific ReportsOpen Access

The interaction network of health-related quality of life in elderly people living with HIV: a cross-sectional study in Chongqing, China

View Full Paper
Ask AI
Bookmark
Share

Authors

BTBo TanChongqing Academy of Environmental ScienceRLRongrong LuMinistry of Education of the People's Republic of ChinaTTTianyu TanChongqing Academy of Environmental Science

Discussion

Loading...

Member takes

Overview

Cross-sectional study uncovers factors influencing quality of life in elderly HIV-positive individuals, suggesting integrated psychosocial care benefits.

Key Points

  • This study aims to characterize the interaction structure of biological, psychological, and social factors affecting health-related quality of life in elderly people living with HIV.
  • Cross-sectional study with 802 HIV-positive individuals aged 50 years or older in Chongqing, China.
  • Applied a mixed graphical model with EBIC selection and LASSO regularization to estimate a network of 17 variables.
  • Computed centrality indices and evaluated stability via bootstrap procedures with 1,000 iterations.
  • Depressive symptoms were central to the network, negatively impacting both physical and mental health domains.
  • Income level and peer support acted as bridge nodes linking various health domains.
  • Observed behavioral clustering between smoking and alcohol use, while clinical indicators like CD4 count and viral load were on the periphery.

Cite This Study

Tan et al. (2026) studied this question.

synapsesocial.com/papers/6a508afd6eeac72a4379ff98https://doi.org/10.1038/s41598-026-59655-9
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regional inequalities in comorbidity patterns among aging HIV populations in China: tales of two cities with distinct HIV dynamics2025
  2. 2The rural-urban disparity in the quality of life among people living with HIV under different household structures in China: a cross-sectional study2025
  3. 3A systematic literature review of quality of life among people living with HIV/AIDS in China2024
  4. 4Direct and indirect factors associated with health-related quality of life among PLHIV on second-line antiretroviral therapy at Dessie and Woldia Comprehensive Specialized Hospitals in Ethiopia: application of structural equation modelling2025
  5. 5Direct and indirect factors associated with health-related quality of life among PLHIV on second-line antiretroviral therapy at Dessie and Woldia Comprehensive Specialized Hospitals in Ethiopia: application of structural equation modelling2026