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July 10, 2026MetabolitesOpen Access

Evaluated School-Based Exercise Interventions with Nutritional Supplementation in Obese Children and Adolescents: A Systematic Review of Randomized Controlled Trials for Highlighting a Research Gap

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Authors

MRMarkel Rico-GonzálezDFDamiano FormentiCGCarlos D. Gómez‐Carmona

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Overview

Systematic review highlights mixed outcomes of exercise and nutritional programs in obese children and adolescents, indicating research gaps.

Key Points

  • This systematic review aims to assess the effects of school-based physical activity and nutritional supplementation programs on obese youth.
  • Conducted a systematic review using the PICOS framework.
  • Reviewed 234 studies across six databases to identify relevant trials involving obese children and adolescents.
  • Assessed included studies using the RoB-2 checklist for risk of bias.
  • Six studies met the inclusion criteria, revealing highly heterogeneous interventions and mixed outcomes.
  • Some benefits were noted for multi-micronutrient supplementation in boys from resource-limited settings, while others showed no effects.
  • Energy-dense supplementation was counterproductive, and methodological limitations call for cautious implementation.

Cite This Study

Rico-González et al. (2026) studied this question.

synapsesocial.com/papers/6a508da76eeac72a437a1035https://doi.org/10.3390/metabo16070477
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Also Consider

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  1. 1The Effects of Physical Activity Programs with Nutritional Supplementation in Children Until 12 Years Old Recruited from Schools: A Systematic Review of Randomized Controlled Trials2025 · 4 citations
  2. 2The Effects of Physical Activity Together With Nutrition Programs in Educational Settings on Obesity and Overweight Reduction in Preschool Children: A Systematic Review of Randomized Controlled Trials2026 · 2 citations
  3. 3The Effects of Nutritional Education and School-Based Exercise Intervention Programs on Preschool and Primary School Children’s Cardiometabolic Biomarkers: A Systematic Review of Randomized Controlled Trials2025
  4. 4Umbrella review of international evidence for the effectiveness of school-based physical activity interventions2024 · 13 citations
  5. 5Overview of systematic reviews on behavioral determinants of physical activity and healthy eating in schoolchildren2025 · 5 citations