Preliminary case series reveals improved facial aesthetics with multimodal rejuvenation protocol, indicating feasibility.
< .001). All patients were rated as "Much Improved" or "Very Much Improved" on GAIS. No serious adverse events occurred. BoNT-A efficacy was clinically preserved throughout follow-up. This multimodal protocol appears to be a feasible and well-tolerated strategy for same-session facial rejuvenation without clinically compromising BoNT-A efficacy.
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Rafael Rodrigo Crisanto de Oliveira (2026) studied this question.
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