Key result
Perioperative blood transfusion is linked to major postoperative complications and reduced overall survival.
Why the study?
Patients aged ≥80 years undergoing lung cancer surgery are at increased risk of morbidity, but risk factors for major postoperative complications and their impact on overall survival needed identification.
What are the risk factors for major postoperative complications and their impact on overall survival in patients aged ≥80 years undergoing lung cancer surgery?
Population
88 patients aged ≥80 years undergoing anatomical lung resections for lung cancer
Comparison
Major complications (TMM ≥ 3) vs minor or no complications (TMM 0–2)
Design
Retrospective cohort study
Authors
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May inform risk stratification in octogenarian lung resections; leaves open whether modifying factors improves survival.
Cohort (n=88)
What are the risk factors for major postoperative complications and their impact on overall survival in patients aged ≥80 years undergoing lung cancer surgery?
p-value: p=0.0009
In octogenarians undergoing lung cancer resection, major postoperative complications and perioperative blood transfusions are associated with significantly impaired survival, whereas minimally invasive surgery is associated with better survival.
Damirov et al. (2026) conducted a cohort in Lung cancer (n=88). Perioperative blood transfusion vs. No perioperative blood transfusion was evaluated on Major postoperative complications (TMM ≥ 3) (p=0.0009). Perioperative blood transfusion was an independent risk factor for major postoperative complications (p=0.0009), which occurred in 27.3% of patients and significantly reduced overall survival.
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