Key result
Poor performance status (P=0.004), major resections (P=0.002), and open surgical approach (P=0.007) were significantly associated with postoperative complications in octogenarians.
Why the study?
Postoperative complication rates remain high after lung cancer surgery in octogenarians, and reports on potential predictors of these complications have shown discordant results.
What are the predictors of postoperative complications in octogenarians undergoing lung cancer surgery?
Population
2,596 octogenarians undergoing lung cancer surgery across 13 cohort studies
Comparison
Potential predictors of postoperative complications
Design
Meta-analysis of cohort studies
Authors
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May guide risk stratification for octogenarians; leaves open prospective validation of minimally invasive approaches.
Meta-Analysis (n=2,596)
What are the predictors of postoperative complications in octogenarians undergoing lung cancer surgery?
p-value: p=0.004 (PS), 0.002 (major resections), 0.007 (open approach)
In octogenarians undergoing lung cancer surgery, poor performance status, major resections, and open surgical approach are significant predictors of postoperative complications.
Bassi et al. (2023) conducted a meta-analysis in Lung cancer (n=2,596). Risk factors (performance status, major resections, open approach) was evaluated on Post-operative complications (p=0.004 (PS), 0.002 (major resections), 0.007 (open approach)). Poor performance status (P=0.004), major resections (P=0.002), and open surgical approach (P=0.007) were significantly associated with postoperative complications in octogenarians.
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