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March 15, 2018PlateletsOpen Access

96-well plate-based aggregometry offers a standardized, portable, and less resource-intensive alternative to traditional light transmission aggregometry for assessing platelet reactivity.

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Comparison

96-well plate-based aggregometry vs Light transmission aggregometry (LTA)

Design

Review

Key result

96-well plate-based aggregometry offers a standardized, portable, and less resource-intensive alternative to traditional light transmission aggregometry for assessing platelet reactivity.

Authors

MCMelissa V. ChanPAPaul C. ArmstrongTWTimothy D. Warner

Discussion

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Overview

May support standardized platelet testing with lower sample volumes; leaves open clinical adoption pending prospective validation.

Structured PICO

I
Intervention
96-well plate-based aggregometry
C
Comparator
Light transmission aggregometry (LTA)
O
Outcome
Standardization and reproducibility of platelet testing

96-well plate-based aggregometry offers a standardized, cost-effective, and portable alternative to traditional light transmission aggregometry for assessing platelet reactivity.

Cite This Study

Chan et al. (2018) conducted a review in Platelet reactivity. 96-well plate-based aggregometry vs. Light transmission aggregometry (LTA) was evaluated. 96-well plate-based aggregometry offers a standardized, portable, and less resource-intensive alternative to traditional light transmission aggregometry for assessing platelet reactivity.

synapsesocial.com/papers/6a518859694df77204bbb9cehttps://doi.org/10.1080/09537104.2018.1445838
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Not all light transmission aggregation assays are created equal: qualitative differences between light transmission and 96-well plate aggregometry2018 · 26 citations
  2. 2Light Transmission Aggregometry and ATP Release for the Diagnostic Assessment of Platelet Function2009 · 186 citations
  3. 3Aggregometry in the settings of thrombocytopenia, thrombocytosis and antiplatelet therapy2018 · 17 citations
  4. 4Standardization of Light Transmission Aggregometry for Diagnosis of Platelet Disorders: An Inter-Laboratory External Quality Assessment2019 · 34 citations
  5. 5Current and emerging approaches for evaluating platelet disorders2016 · 19 citations