Key result
Single slice VAT area at L2-L3 was significantly better correlated with total VAT volume than L4-L5 area (r=0.96 vs 0.83; P<0.001) across all levels of obesity and in both genders.
Why the study?
Does single slice MR image VAT area accurately predict total VAT volume in overweight and obese subjects?
Population
668 untreated sleep apnea subjects enrolled in the Icelandic Sleep Apnea Cohort, overweight and obese.
Comparison
Single slice MR image VAT area at L2-L3 and… vs Total VAT volume by abdominal MRI (gold-standard)
Design
Cross-sectional
Authors
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Single-slice L2-L3 VAT area reliably surrogates total volume in obese adults; supports cost-effective research protocols but leaves clinical adoption open pending trials.
Cohort (n=668)
Does single slice MR image VAT area accurately predict total VAT volume in overweight and obese subjects?
Absolute Event Rate: 0.96% vs 0.83%
p-value: p=<0.001
Single slice MR imaging at the L2-L3 interspace is a highly reliable surrogate for total visceral adipose tissue volume across all levels of obesity in both genders.
Maislin et al. (2012) conducted a cohort in Overweight and obese with untreated sleep apnea (n=668). Single slice MR image VAT area at L2-L3 vs. Single slice MR image VAT area at L4-L5 was evaluated on Correlation with total VAT volume (95% CI 0.11-0.15, p=<0.001). Single slice VAT area at L2-L3 was significantly better correlated with total VAT volume than L4-L5 area (r=0.96 vs 0.83; P<0.001) across all levels of obesity and in both genders.
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