What question did this study set out to answer?

To evaluate the accuracy of single- and multi-slice segmented MRI areas at specific anatomical landmarks for predicting total visceral adipose tissue volume in morbidly obese individuals across age and sex.

March 24, 2016Scientific ReportsOpen Access

Age and gender specific estimation of visceral adipose tissue amounts from radiological images in morbidly obese patients

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Morbid obesity (n=130). Intervention: Segmented VAT areas from single or five adjacent MRI slices vs. Measured total VAT volume. Primary outcome: Standard deviation of differences between predicted and measured total VAT volume.

View Full Paper

Ask AI

Bookmark

Key result

Total visceral adipose tissue volumes in morbidly obese patients can be reliably predicted from segmented VAT areas at gender-specific lumbar reference levels (L3-L4 for females, L1-L2 for males).

Why the study?

Can total visceral adipose tissue volume be reliably predicted from single or five adjacent MRI slices in morbidly obese patients?

Key Points

To evaluate the accuracy of single- and multi-slice segmented MRI areas at specific anatomical landmarks for predicting total visceral adipose tissue volume in morbidly obese individuals across age and sex.
Analyzed MRI scans from 130 morbidly obese patients (mean BMI 46.5 kg/m²; 94 females) covering approximately 40 axial slices from the diaphragm to the pelvic floor.
Predicted total visceral adipose tissue (VAT) volume from segmented areas using single-slice (σ1) and five-slice (σ5) acquisitions across standard spinal landmark levels.
Total measured VAT volume averaged 4.9 L in females and 8.1 L in males.
The most accurate prediction levels occurred at L3–L4 for females (σ5 = 688 ml, σ1 = 832 ml) and L1–L2 for males (σ5 = 846 ml, σ1 = 992 ml), independent of patient age.

Study Design

Type

Cross-Sectional (n=130)

Multicenter

Structured PICO

Can total visceral adipose tissue volume be reliably predicted from single or five adjacent MRI slices in morbidly obese patients?

Population

130 morbidly obese Caucasian adults (BMI > 40 kg/m2, 72.3% female) underwent MRI to evaluate the predictive power of partial VAT areas for total VAT volume.

Exposure

Estimation of total visceral adipose tissue (VAT) volume from segmented VAT areas of single or five adjacent MRI slices at specific anatomical landmarks.

Comparator

Measured total VAT volume (VVAT-T) calculated from about 40 slices between diaphragm and pelvic floor.

Outcome

Agreement between predicted and measured total VAT volumes, assessed by standard deviations of volume differences and coefficient of determination (R2).surrogate

Total visceral adipose tissue volume in morbidly obese patients can be reliably estimated using a single or five-slice MRI approach at gender-specific lumbar reference levels.

Limitations

Retrospective, single-centre design
Higher number of females than males, meaning findings in males should be interpreted more carefully
Retrospective design
Single-center design
Higher number of females than males

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May simplify single-slice VAT estimation in morbid obesity; leaves open prospective validation before wider use.

Cite This Study

Linder et al. (2016) conducted a cross-sectional in Morbid obesity (n=130). Segmented VAT areas from single or five adjacent MRI slices vs. Measured total VAT volume was evaluated on Standard deviation of differences between predicted and measured total VAT volume. Total visceral adipose tissue volumes in morbidly obese patients can be reliably predicted from segmented VAT areas at gender-specific lumbar reference levels (L3-L4 for females, L1-L2 for males).

synapsesocial.com/papers/6a74aa88a44b96c1f7dbdd2e https://doi.org/10.1038/srep22261

View Full Paper

Ask AI

Bookmark

Age and gender specific estimation of visceral adipose tissue amounts from radiological images in morbidly obese patients

Key Points

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Age and gender specific estimation of visceral adipose tissue amounts from radiological images in morbidly obese patients

Key Points

Study Design

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider