Key result
Aspirin 100 mg daily led to the resolution of an aortic valve strand within 10 days in a 21-year-old man with acute ischemic stroke, with no recurrent stroke over a 3-year follow-up.
Why the study?
Does aspirin therapy resolve native valvular strands and prevent recurrent stroke in a patient with acute ischemic stroke?
Case Report (n=1)
Does aspirin therapy resolve native valvular strands and prevent recurrent stroke in a patient with acute ischemic stroke?
Aspirin therapy may be associated with the resolution of native valvular strands and prevention of recurrent cardioembolic stroke.
Native valvular strands merit consideration in young stroke etiology; leaves open optimal monitoring or therapy.
Valvular strands are known to be a potential source of cardioembolism but the natural history of native valvular strands has not yet been fully outlined. We report a case of ischemic stroke in a patient with a native valvular strand of the aortic valve and the patient's clinical course. A previously healthy 21-year-old man suffered acute cerebral infarction in the right posterior cerebral artery territory. On echocardiography, there was a strand-like, oscillating mass on the left coronary cusp of the aortic valve. The patient received 100 mg aspirin daily and the valvular strand was not found on subsequent transthoracic echocardiography performed 10 days after the first examination. Serial echocardiographic examinations have been performed since the stroke and failed to find any abnormality. The patient did not suffer a recurrent stroke over a 3-year follow-up period.
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Rhee et al. (2010) conducted a case report in Acute ischemic stroke with a native valvular strand (n=1). Aspirin was evaluated on Recurrent stroke and resolution of valvular strand. Aspirin 100 mg daily led to the resolution of an aortic valve strand within 10 days in a 21-year-old man with acute ischemic stroke, with no recurrent stroke over a 3-year follow-up.
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