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mRNA processing, e.g., 3' end polishing, and for mRNA analysis in combination with liquid chromatography-tandem mass spectrometry (LC-MS/MS). Applications of the latter include the comprehensive assessment of 5' capping efficiency, 3' poly(A) tail length and composition, one-pot multiplexed cleavage for RNA sequencing, modification detection, and fingerprinting.
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Liu et al. (2026) studied this question.
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