What question did this study set out to answer?

This study aims to explore how depressive symptoms mediate the relationship between loneliness and subjective memory complaints, with an emphasis on the moderating role of meaning in life.

July 11, 2026Psychiatry InvestigationOpen Access

Loneliness, Depression, and Subjective Memory Complaints in Middle-Aged and Older Adults: The Role of Meaning in Life

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This study aims to explore how depressive symptoms mediate the relationship between loneliness and subjective memory complaints, with an emphasis on the moderating role of meaning in life.
Cross-sectional survey with 580 adults aged 41–71 years from Korea
Participants assessed for loneliness, depression, subjective memory complaints, and meaning in life
Mediation and moderated mediation analyses performed using 5,000 bootstrap resamples
Loneliness significantly associated with depression (β=0.523, p<0.001) and subjective memory complaints (β=0.131, p=0.008)
Depression partially mediates the relationship between loneliness and SMCs (indirect effect=0.011; 95% CI [0.006, 0.018])
Meaning in life buffers the loneliness-depression association, with interaction showing stronger effects at low MIL (B=0.237) than high MIL (B=0.148)

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Implication

Cross-sectional survey investigates the impact of loneliness and depression on memory complaints, emphasizing life's meaning in older adults.

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/6a51ddbfc18d7f28ca5000e7 https://doi.org/10.30773/pi.2025.0326

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Implication

Cross-sectional survey investigates the impact of loneliness and depression on memory complaints, emphasizing life's meaning in older adults.

Loneliness, Depression, and Subjective Memory Complaints in Middle-Aged and Older Adults: The Role of Meaning in Life

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Discussion

Implication

Cite This Study

Loneliness, Depression, and Subjective Memory Complaints in Middle-Aged and Older Adults: The Role of Meaning in Life

Key Points

Discussion

Implication

Cite This Study

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