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July 11, 2026Regional Anesthesia & Pain Medicine

Evaluating the effectiveness of bilateral erector spinae plane blocks in addition to standard multimodal analgesia at reducing opioid consumption in patients undergoing elective mammoplasty in an ambulatory surgical center: a randomized clinical trial

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Authors

RKRafi KhandakerAlbert Einstein College of MedicineTRTanzib RazzakiUniversity of Rochester Medical CenterMAMelinda AquinoMontefiore Medical Center

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Overview

Randomized trial evaluates opioid consumption in patients receiving ESP block versus standard analgesia, suggesting limited benefit.

Key Points

  • This trial aimed to assess the effectiveness of erector spinae plane blocks in reducing opioid usage during recovery from elective mammoplasty surgery.
  • 78 patients were randomized to receive either bilateral erector spinae plane blocks or standard multimodal analgesia.
  • The ESP block group received ultrasound-guided blocks at the T4 level with 30 mL of 0.25% ropivacaine per side.
  • Outcome measures included opioid consumption, discharge times, and postoperative satisfaction.
  • The ESP group used an average of 10.6 mg oral morphine equivalents versus 17.5 mg in the control group (p=0.014).
  • Mean discharge time was shorter for the block group (170 min) compared to the control group (213 min, p=0.012).
  • Opioid requirement was lower in the block group, with 59% needing opioids versus 86.8% in the control group (p=0.006).

Cite This Study

Khandaker et al. (2026) studied this question.

synapsesocial.com/papers/6a51deadc18d7f28ca500628https://doi.org/10.1136/rapm-2026-107819
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Erector spinae plane block for breast surgery: an umbrella review of systematic reviews and meta-analyses2025 · 2 citations
  2. 2Ultrasound-guided erector spinae plane block versus paravertebral block for postoperative analgesia in mastectomy and immediate breast reconstruction: a randomized non-inferiority trail2026
  3. 3Erector Spinae Plane Block Versus PECS Block Type II for Breast Surgery: A Randomized Controlled Trial2022 · 23 citations
  4. 4Comparison of erector spinae plane block and rhomboid intercostal block for postoperative pain management in patients undergoing unilateral breast surgery2026
  5. 5Erector Spinae Plane versus Pectoralis Nerve Block for Mastectomy in Cancer Patients: A Retrospective, Multicenter Cohort Study2025 · 1 citations