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September 17, 2025Journal of Pain ResearchOpen Access

Erector Spinae Plane versus Pectoralis Nerve Block for Mastectomy in Cancer Patients: A Retrospective, Multicenter Cohort Study

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Authors

EYEdward N. YapJWJulia WeiCDCurtis Darling

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Overview

Retrospective cohort study finds no difference in opioid use for mastectomy patients using ESP or PECS blocks.

Key Points

  • No significant difference in total opioid use was observed between the ESP and PECS block groups, suggesting similar efficacy for pain management.
  • Median total opioid use was 53 MME for ESP and 60 MME for PECS during hospital stay, indicating comparable pain control strategies.
  • The cohort study analyzed 517 breast cancer patients, contributing to findings on postoperative analgesia from 2017 to 2020.
  • Results show that both blocks maintain similar postoperative outcomes, including pain scores and hospital discharge times.

Cite This Study

Yap et al. (2025) studied this question.

synapsesocial.com/papers/68d46ccf31b076d99fa6917fhttps://doi.org/10.2147/jpr.s538581
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of erector spinae plane, paravertebral, and pectoral nerve blocks on postoperative analgesia and Quality of Recovery-15 in patients undergoing mastectomy: a prospective randomized trial2026
  2. 2Erector Spinae Plane Block Versus PECS Block Type II for Breast Surgery: A Randomized Controlled Trial2022 · 23 citations
  3. 3Comparative Study for Efficacy of Ultrasound Guided Pectoral Nerve Block versus Erector Spinae Plane Block for Post Operative Analgesia in Modified Radical Mastectomy2025
  4. 4COMPARISON OF POSTOPERATIVE ANALGESIC EFFECT OF ULTRASOUND GUIDED PECTORAL VS ERECTOR SPINAE BLOCK IN PATIENTS UNDERGOING MODIFIED RADICAL MASTECTOMY2024
  5. 5Ultrasound-guided erector spinae plane block versus paravertebral block for postoperative analgesia in mastectomy and immediate breast reconstruction: a randomized non-inferiority trail2026