Key result
Complex congenital heart disease, pulmonary hyperperfusion, and LVEF <55% predict in-hospital mortality and cardiovascular events.
Why the study?
What are the disease burden trends and risk factors for in-hospital mortality and cardiovascular events in patients with congenital heart disease combined with heart failure in China?
What are the disease burden trends and risk factors for in-hospital mortality and cardiovascular events in patients with congenital heart disease combined with heart failure in China?
The disease burden of congenital heart disease combined with heart failure in China is increasing, with specific clinical factors like complex CHD and LVEF <55% independently predicting in-hospital mortality and cardiovascular events.
Rising CHD-HF burden in older Chinese adults supports monitoring; leaves open whether identified risk factors guide interventions.
The disease burden of CHD combined with HF in China has shown a continuous upward trend from 1990 to 2021, with higher growth rates in older age groups. Complex CHD, pulmonary hyperperfusion, left ventricular ejection fraction <55%, arterial oxygen partial pressure, and serum calcium concentration are independent risk factors for in-hospital mortality and cardiovascular events.
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Sheng et al. (2025) studied this question. Complex congenital heart disease, pulmonary hyperperfusion, LVEF <55%, arterial oxygen, and serum calcium are independent risk factors for in-hospital mortality and cardiovascular events.
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