Association between Variation of Troponin and Prognosis of Acute Myocardial Infarction before and after Primary Percutaneous Coronary Intervention

Figures

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  Figure 1. Flow chart of study enrollment. cTnI, cardiac troponin I; PPCI, primary percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction.

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  Figure 2. The time of the second sample taken after primary PCI. There were 509 (44.728%) cases measured immediately after PPCI and 606 (53.251%) measured during the index hospitalization. Five hundred and nine (44.728%) cases were measured at the same day of primary PCI and the cases measured during 0–7 days were 560 (49.209%).

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  Figure 3. Survival ROC curve. Predictive value 1: predictive values of ratio of delta cTnI to cTnI measured prior PPCI; predictive value 2: predictive values of delta cTnI; predictive value 3: predictive values of the peak cTnI level after PPCI; and predictive value 4: predictive values of the first admission cTnI level. Survival receiver operating characteristic curves for a model including the ratio of delta cTnI to cTnI measured prior PPCI (black line), △cTnI level (wathet blue line), peak level after PPCI (red line), and cTnI concentrations at admission (dark blue line). The areas under the ROC curve are shown for the graph. AUC, area under the curve; ROC, survival receiver operating characteristic; TP, true positive; and FP, false positive.

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  Figure 4. Cumulative incidence of myocardial infarction or cardiac death in patients with troponin concentrations. Patients were stratified into four groups based on the △cTnI level. Q1: first quartile (green line); Q2: second quartile (blue line); Q3: third quartile (grey line); and Q4: fourth quartile (black line). (a) Kaplan–Meier curves depicting the cumulative probability for MACE (log rank p = 0.035). (b) Kaplan–Meier curves depicting the cumulative probability for mortality (log rank p = 0.049). (c) Kaplan–Meier curves depicting the cumulative probability for recurrent myocardial infarction (log rank p = 0.150). (d) Kaplan–Meier curves depicting the cumulative probability for angina pectoris (log rank p = 0.026). MACE: major adverse cardiovascular events.