Key result
Yoga Nidra improves sleep efficiency by ~28% vs standard care in stable CAD.
Why the study?
Poor sleep quality worsens prognosis in CAD, while sleep aids increase adverse events. The study evaluated the adjunctive effect of Yoga Nidra on actigraphy-measured sleep quality, psychological outcomes, and quality of life in CAD patients.
Does a 12-week Yoga Nidra intervention improve actigraphy-measured sleep efficiency in patients with stable coronary artery disease and poor sleep quality?
RCT (n=144)
Open-label, blinded-endpoint
1:1 allocation
No
Does a 12-week Yoga Nidra intervention improve actigraphy-measured sleep efficiency in patients with stable coronary artery disease and poor sleep quality?
Absolute Event Rate: 82% vs 64%
p-value: p=< 0.05
A 12-week Yoga Nidra intervention significantly improves objective sleep parameters and psychological health in patients with stable CAD and poor sleep quality.
Supports Yoga Nidra integration into CAD care for sleep; extends RCT evidence for mind-body interventions.
Background Poor sleep quality has emerged as a risk for coronary artery disease (CAD) and is also associated with poor prognosis and increased mortality. Sleep aids, among CAD patients, lead to increased heart failure, hospitalisation, and mortality. Yoga Nidra, a form of guided meditation, has been shown to improve sleep quality and duration. The aim of the study is to evaluate the adjunctive effect of Yoga Nidra on actigraphy-measured sleep quality parameters, psychological outcomes, and health-related quality of life in patients with CAD. Methods This is a two-arm,1:1 allocation, randomised, controlled, open-label, blinded-endpoint, single-centre trial conducted in a tertiary care hospital between 22-9-2021 and 30-03-2024.144 out of 678 consecutively screened patients with stable CAD and poor sleep quality met the eligibility criteria and were enrolled. Participants were randomised to either a 35-minute, 12-week Yoga Nidra intervention group (n = 72) or a standard care group (n = 72) with sleep hygiene counselling imparted to all patients.The primary outcome was to assess actigraphy-measured sleep efficiency. Secondary outcomes included assessments of actigraphy-derived sleep parameters, ambulatory blood pressure (BP), echocardiographic diastolic function (E/E′), psychological health, and quality-of-life evaluations using validated scales. Results The Yoga Nidra group exhibited significant improvements in sleep efficiency (82% [76-86] vs. 64% [57-74]; p < 0.05), total sleep time (357 ± 99 min vs. 298 ± 83 min; p < 0.05), reduced sleep latency (15 [11-24] vs. 30 [14-70] min; p < 0.05), and lower wake after sleep onset (48 [28-67] vs. 67 [37-119] min; p < 0.05). Significant improvements were also observed in perceived stress, depression levels, and quality of life. Conclusion Yoga Nidra is effective in improving sleep quality inpatients with coronary artery disease.Stress, depression, and health-related quality of life also improved with Yoga Nidra.
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Sharma et al. (2026) conducted an RCT in Coronary artery disease (n=144). Yoga Nidra vs. Standard care with sleep hygiene counselling was evaluated on Actigraphy-measured sleep efficiency (p=< 0.05). A 12-week Yoga Nidra intervention significantly improved actigraphy-measured sleep efficiency compared to standard care in patients with stable coronary artery disease (82% vs. 64%; p < 0.05).
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