Answers are grounded in this paper and cite their sources.
Compares sedation and anxiety reduction in children using melatonin and triclofos sodium, suggesting effective premedication options.
Objectives: To compare the pre- and post-use of oral melatonin and oral triclofos as oral sedative drugs on anxiety, sedation, and cognitive and psychomotor function to perform satisfactory dental treatment on uncooperative children. Methods: A total number of 100 patients aged between 4 and 9 years who were scheduled for dental treatment were randomly divided into two groups, Group I and Group II, and administered melatonin and triclofos sodium, respectively, to determine changes in anxiety, cognitive, psychomotor, and sedation scores pre- and post-treatment. Data were analyzed using an unpaired/paired t-test, and P < 0.05 was contemplated as statistically significant. Results: Post-treatment assessments revealed a significant reduction in cognitive and anxiety scores, alongside an increase in sedation scores observed 60 minutes after administration of melatonin and triclofos. Upon comparison, melatonin demonstrated a superior sedative effect and a greater reduction in anxiety levels compared to triclofos sodium; however, these differences were not statistically significant. Conclusion: Both melatonin and triclofos sodium are pharmacologically effective agents that may serve as potent premedication options for alleviating anxiety associated with dental procedures.
No takes yet. Share an insight, caveat, or question.
Shrivastava et al. (2026) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: