Characterizes genotypic distribution of C. pneumoniae ST16 in France, suggesting clonal expansion.
A resurgence of Chlamydia pneumoniae respiratory infections was observed in France during 2024–2025. We aimed to characterise the genotypic distribution of C. pneumoniae during the outbreak period using positive respiratory samples from infected individuals. Molecular typing was performed by applying the Chlamydiales Multi-Locus Sequence Typing (MLST) scheme. Our results revealed the exclusive predominance of C. pneumoniae ST16, suggesting dissemination of ST16 across France. Further molecular analyses of isolates from other countries are needed to determine whether the recent resurgence of C. pneumoniae infections is driven by clonal expansion.
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