Key result
A 61-year-old woman was diagnosed with the first reported case of synchronous intravascular large B-cell lymphoma involving a gastrointestinal stromal tumor, and died 4 months after surgery.
Case Report (n=1)
This represents the first reported case of synchronous intravascular large B-cell lymphoma involving a gastrointestinal stromal tumor.
May prompt consideration of lymphoma in atypical GIST with fever of unknown origin; leaves open questions on pathogenesis and management.
BACKGROUND: Intravascular large B-cell lymphoma is a rare and aggressive lymphoma with a dismal prognosis. Synchronous intravascular large B-cell lymphoma involving gastrointestinal stromal tumor has not previously been documented. CASE PRESENTATION: We report a case of a 61-year-old Chinese woman who presented with high fever of unknown origin for 20 days, and hematemesis, melena for 2 days. A computed tomography scan revealed a mass lesion located in the anterior wall of the stomach. Surgery was performed to remove the tumor and histopathology showed a gastrointestinal stromal tumor and a synchronous intravascular large B-cell lymphoma. The patient refused further treatment and died 4 months after surgery. CONCLUSIONS: To the best of our knowledge, this case represents the first report of synchronous intravascular large B-cell lymphoma involving a gastrointestinal stromal tumor.
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Zhang et al. (2015) conducted a case report in Synchronous intravascular large B-cell lymphoma involving gastrointestinal stromal tumor (n=1). Partial gastrectomy was evaluated. A 61-year-old woman was diagnosed with the first reported case of synchronous intravascular large B-cell lymphoma involving a gastrointestinal stromal tumor, and died 4 months after surgery.
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