Key result
Combined use of PAI-1 plasma activity and T1-201-perfusion imaging 3 months after angioplasty predicted angiographic restenosis at 6 months with 67% sensitivity and 85% specificity.
Why the study?
Does the combination of PAI-1 plasma activity and T1-201-perfusion imaging predict angiographic restenosis in asymptomatic patients 3 months after successful PTCA?
Population
25 asymptomatic patients with single vessel disease who had successful percutaneous transluminal coronary…
Design
Cohort
Follow-up
6 months
Authors
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Changes in PAI-1 and thallium imaging may predict post-PTCA restenosis; leaves open prospective validation before clinical adoption.
Cohort (n=25)
Does the combination of PAI-1 plasma activity and T1-201-perfusion imaging predict angiographic restenosis in asymptomatic patients 3 months after successful PTCA?
The combined use of PAI-1 plasma activity and T1-201-perfusion imaging 3 months post-PTCA improves the prediction of angiographic restenosis in asymptomatic patients.
Gottsauner‐Wolf et al. (1999) conducted a cohort in Restenosis after percutaneous transluminal coronary angioplasty (PTCA) (n=25). PAI-1 plasma activity and Thallium perfusion imaging was evaluated on Angiographic restenosis (percent diameter stenosis >50%) at 6 months. Combined use of PAI-1 plasma activity and T1-201-perfusion imaging 3 months after angioplasty predicted angiographic restenosis at 6 months with 67% sensitivity and 85% specificity.
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