January 1, 1992Thrombosis and Haemostasis
A Decrease in Plasminogen Activator Inhibitor-1 Activity after Successful Percutaneous Transluminal Coronary Angioplasty Is Associated with a Significantly Reduced Risk for Coronary Restenosis
View Full Paper
Ask AI
Bookmark
Share
Why the study?
Is a decrease in PAI-1 activity after successful PTCA associated with a reduced risk of coronary restenosis in patients with low grade residual stenosis?
Population
104 patients with a low grade residual stenosis after successful percutaneous transluminal coronary…
Comparison
Decrease in plasminogen activator inhibitor-1… vs Increase in PAI-1 plasma levels over time
Design
Cohort
Follow-up
12 months
Authors
Discussion
Loading...
Member takes
Implication
Decrease in PAI-1 after PTCA was associated with lower restenosis; hypothesis-generating and leaves open whether targeting PAI-1 alters outcomes.
Structured PICO
Is a decrease in PAI-1 activity after successful PTCA associated with a reduced risk of coronary restenosis in patients with low grade residual stenosis?
P
Population
104 patients with a low grade residual stenosis (<30%) after successful percutaneous transluminal coronary angioplasty (PTCA)
I
Intervention
Decrease in plasminogen activator inhibitor-1 (PAI-1) plasma levels over time
C
Comparator
Increase in PAI-1 plasma levels over time
O
Outcome
Angiographically proven coronary restenosissurrogate
A decrease in PAI-1 activity following successful PTCA is associated with a significantly reduced risk of subsequent angiographic coronary restenosis.
Cite This Study
Huber et al. (1992) studied this question.
View Full Paper
Ask AI
Bookmark
Share