Key result
Acute myocardial infarction was associated with significantly greater plasma and platelet PAI-1 concentrations on day 1 compared to patients with or without stable coronary artery disease.
Population
72 subjects who underwent coronary angiography, divided into CAD without coronary artery stenosis or…
Design
Cohort
Follow-up
28 days (for AMI group)
Authors
Loading...
Elevated PAI-1 in early AMI may heighten thrombotic risk; hypothesis-generating for targeted inhibition, pending prospective trials.
Observational (n=72)
Elevated platelet and plasma PAI-1 levels at the onset of AMI suggest that PAI-1 accumulated in platelets may be released into plasma, potentially contributing to increased thrombus formation.
Soeki et al. (2000) conducted an observational in Acute Myocardial Infarction and Coronary Artery Disease (n=72). Acute myocardial infarction vs. Patients with or without stable coronary artery disease was evaluated on Plasma and platelet PAI-1 concentrations. Acute myocardial infarction was associated with significantly greater plasma and platelet PAI-1 concentrations on day 1 compared to patients with or without stable coronary artery disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: