Key result
Untreated white coat hypertension was associated with an increased risk for cardiovascular events compared with normotension (HR 1.36; 95% CI 1.03-2.00).
Why the study?
The long-term cardiovascular risk of isolated elevated office blood pressure was unclear.
Does untreated white coat hypertension or treated white coat effect increase the risk of cardiovascular events and mortality compared to normotension?
Meta-Analysis (n=64,273)
Does untreated white coat hypertension or treated white coat effect increase the risk of cardiovascular events and mortality compared to normotension?
Hazard Ratio: 1.36 (95% CI 1.03–2)
Untreated white coat hypertension is associated with an increased risk for cardiovascular events and mortality, whereas treated white coat effect is not, emphasizing the need for out-of-office BP monitoring.
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Supports monitoring untreated white coat hypertension; leaves open treatment effects pending randomized trials.
Cohen et al. (2019) conducted a meta-analysis in White Coat Hypertension (n=64,273). Untreated white coat hypertension (WCH) vs. Normotension was evaluated on Cardiovascular events (HR 1.36, 95% CI 1.03 to 2.00). Untreated white coat hypertension was associated with an increased risk for cardiovascular events compared with normotension (HR 1.36; 95% CI 1.03-2.00).
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