Key result
White-coat hypertension was associated with higher cardiovascular morbidity and mortality compared with normotension, but risks were significantly lower than those associated with sustained hypertension.
Why the study?
Does white-coat hypertension increase the risk of cardiovascular events and mortality compared with normotension and sustained hypertension?
Systematic Review (n=29,100)
Does white-coat hypertension increase the risk of cardiovascular events and mortality compared with normotension and sustained hypertension?
White-coat hypertension is associated with a slightly higher risk of cardiovascular morbidity and mortality compared to normotension, but a significantly lower risk compared to sustained hypertension.
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Affirms need for out-of-office BP confirmation in risk assessment; leaves open whether intervention improves outcomes in white-coat hypertension.
Briasoulis et al. (2016) conducted a systematic review in White-coat hypertension (n=29,100). White-coat hypertension vs. Normotension and sustained hypertension was evaluated on Cardiovascular events and death, stroke, and all-cause mortality. White-coat hypertension was associated with higher cardiovascular morbidity and mortality compared with normotension, but risks were significantly lower than those associated with sustained hypertension.
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