What is the clinical evidence from this study?

Study design: Observational. Population: Paroxysmal atrial fibrillation (n=34). Intervention: P wave polarity on surface ECG. Primary outcome: Predicting an arrhythmogenic focus of AF from the superior vena cava (Sensitivity 71%, Specificity 82%).

April 1, 2003Journal of Cardiovascular Electrophysiology

P Wave Polarities of an Arrhythmogenic Focus in Patients with Paroxysmal Atrial Fibrillation Originating from Superior Vena Cava or Right Superior Pulmonary Vein

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Key result

A biphasic or isoelectric P wave in lead V1 or a biphasic P wave in lead aVL predicted an atrial fibrillation focus from the superior vena cava with 71% sensitivity and 82% specificity.

Why the study?

Does P wave polarity on surface ECG help distinguish an arrhythmogenic focus of paroxysmal atrial fibrillation from the superior vena cava versus the right superior pulmonary vein?

Population

34 patients with paroxysmal atrial fibrillation originating from the superior vena cava or right superior…

Comparison

12-lead ECG analysis of P wave polarities during… vs Comparison between arrhythmogenic foci…

Design

Cohort

Authors

JKJEN‐YUAN KUOMackay Memorial Hospital CTCHING‐TAI TAIFu Jen Catholic University HTHSUAN‐MING TSAONational Yang Ming Chiao Tung University

Discussion

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Implication

Specific P wave polarities in leads V1 and aVL on a standard 12-lead ECG can help differentiate paroxysmal atrial fibrillation triggers originating from the superior vena cava versus the right superior pulmonary vein.

Study Design

Type

Observational (n=34)

Structured PICO

Does P wave polarity on surface ECG help distinguish an arrhythmogenic focus of paroxysmal atrial fibrillation from the superior vena cava versus the right superior pulmonary vein?

Population

34 patients with paroxysmal atrial fibrillation originating from the superior vena cava or right superior pulmonary vein who underwent electrophysiologic study and ablation.

Exposure

12-lead ECG analysis of P wave polarities (specifically leads I, aVR, aVL, and V1) during sinus rhythm and ectopic beats.

Comparator

Comparison between arrhythmogenic foci originating from the superior vena cava (SVC) versus the right superior pulmonary vein (RSPV).

Outcome

Diagnostic accuracy (sensitivity, specificity, positive predictive value, and negative predictive value) of P wave polarity in predicting an arrhythmogenic focus of AF from SVC or RSPV.surrogate

Main Result

Effect estimate: Sensitivity 71%, Specificity 82%

Cite This Study

KUO et al. (2003) conducted an observational in Paroxysmal atrial fibrillation (n=34). P wave polarity on surface ECG was evaluated on Predicting an arrhythmogenic focus of AF from the superior vena cava (Sensitivity 71%, Specificity 82%). A biphasic or isoelectric P wave in lead V1 or a biphasic P wave in lead aVL predicted an atrial fibrillation focus from the superior vena cava with 71% sensitivity and 82% specificity.

synapsesocial.com/papers/6a557f06cae1d55e053ea8bb https://doi.org/10.1046/j.1540-8167.2003.02513.x

Topics

Atrial fibrillation Persistent AF management AF ablation outcomes

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P Wave Polarities of an Arrhythmogenic Focus in Patients with Paroxysmal Atrial Fibrillation Originating from Superior Vena Cava or Right Superior Pulmonary Vein

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Cite This Study

Topics

P Wave Polarities of an Arrhythmogenic Focus in Patients with Paroxysmal Atrial Fibrillation Originating from Superior Vena Cava or Right Superior Pulmonary Vein

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Cite This Study

Also Consider

Topics

Also Consider