Study: Typical methadone doses not adequate for fentanyl users

People who use illicit fentanyl are tolerant to typical doses of methadone and would require at least 10 times the amount of methadone they get, according to a study published last month in Drug and Alcohol Dependence . The study, “Estimating the Daily Milligrams of Morphine Equivalent of Illicit Fentanyl Use in Los Angeles: Clinical and Epidemiological Implications” by Morgan Godvin and colleagues, used data from a community‐based drug checking service in Los Angeles assess the purity of 509 samples of fentanyl collected between 2023 to 2026. The study revealed the following results.