Key result
Hypersensitivity reactions to cardiac implantable electronic devices are rare but should be suspected in patients presenting with recurrent wound complications and no signs of infection.
Why the study?
Hypersensitivity to metallic and nonmetallic components of CIEDs remains a clinical concern that is rare, not fully understood, and challenging to diagnose and treat.
Cardiologists should consider delayed-type hypersensitivity when a patient with a CIED presents with recurrent wound complications but without signs of infection.
Advances in cardiac implantable electronic devices (CIEDs) have prolonged life expectancy in various medical settings. However, the issue of hypersensitivity to components of CIEDs is still a concern. Since 1970, allergic reactions to metallic and nonmetallic components of CIEDs have been reported. Hypersensitivity reactions to medical devices are rare and not fully understood. In some cases, diagnosis and treatment are difficult. Cardiologists should always keep in mind pacemaker allergy when a patient appears with wound complications and no signs of infection. Patch testing should be tailored toward the specific biomaterials used in a device, in addition to testing with standard screening allergens in select cases.
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Ruvo et al. (2023) conducted a review in Cardiac implantable electronic device (CIED) hypersensitivity. Cardiac implantable electronic devices (CIEDs) was evaluated. Hypersensitivity reactions to cardiac implantable electronic devices are rare but should be suspected in patients presenting with recurrent wound complications and no signs of infection.
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