Key result
Cardiac MR elastography-measured left ventricular shear-wave amplitudes were significantly lower in patients with diastolic dysfunction compared to controls (P<0.001), yielding an AUC of 0.92.
Why the study?
Does cardiac MR elastography-measured shear-wave amplitude accurately diagnose diastolic dysfunction compared to asymptomatic controls?
Cross-Sectional (n=50)
Does cardiac MR elastography-measured shear-wave amplitude accurately diagnose diastolic dysfunction compared to asymptomatic controls?
Effect estimate: AUC 0.92
p-value: p=<.001
Cardiac MR elastography-measured left ventricular shear-wave amplitude is significantly reduced in patients with diastolic dysfunction and provides high diagnostic accuracy.
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May support noninvasive diastolic dysfunction detection; leaves open validation in larger prospective studies.
Elgeti et al. (2014) conducted a cross-sectional in Diastolic dysfunction (n=50). Cardiac MR elastography vs. Asymptomatic healthy volunteers was evaluated on Normalized mean left ventricular shear-wave amplitude (AUC 0.92, p=<.001). Cardiac MR elastography-measured left ventricular shear-wave amplitudes were significantly lower in patients with diastolic dysfunction compared to controls (P<0.001), yielding an AUC of 0.92.
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