Key result
Cardiac MRE detects ~39% lower LV wave amplitudes in patients with mild relaxation abnormalities.
Why the study?
The potential of cardiac magnetic resonance elastography for elasticity-based detection of abnormal left ventricular relaxation was not established.
Does cardiac magnetic resonance elastography (MRE) detect abnormal left ventricular relaxation in patients compared to healthy volunteers?
Cross-Sectional (n=27)
Does cardiac magnetic resonance elastography (MRE) detect abnormal left ventricular relaxation in patients compared to healthy volunteers?
Absolute Event Rate: 0.14% vs 0.23%
Cardiac MRE identifies significantly reduced LV shear wave amplitudes in patients with mild relaxation abnormalities, suggesting its potential as an elasticity-based diagnostic tool.
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MRE may identify mild LV relaxation abnormalities; leaves open its diagnostic utility pending prospective validation.
Elgeti et al. (2010) conducted a cross-sectional in Abnormal left ventricular relaxation (n=27). Cardiac magnetic resonance elastography (MRE) vs. Healthy volunteers was evaluated on Mean wave amplitudes in the left ventricle. Cardiac magnetic resonance elastography identified significantly reduced LV shear wave amplitudes in patients with mild relaxation abnormality (0.14 mm) compared to older volunteers (0.23 mm).
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