Key result
Multimodality imaging could improve patient selection for implantable cardioverter-defibrillators in heart failure beyond left ventricular ejection fraction by concentrating on arrhythmic substrate.
Why the study?
Although implantable cardioverter-defibrillators reduce mortality in heart failure, the benefit appears uneven, prompting the need for better risk stratification.
Does multimodality imaging improve patient selection for ICD implantation in heart failure patients compared to selection using only LVEF?
Does multimodality imaging improve patient selection for ICD implantation in heart failure patients compared to selection using only LVEF?
Multimodality imaging offers a promising approach to refine risk stratification and patient selection for ICD therapy in heart failure beyond LVEF alone.
Answers are grounded in this paper and cite their sources.
May refine ICD selection in HF beyond LVEF; leaves open prospective validation of outcomes.
Advanced pharmacologic and interventional therapies have improved survival in heart failure. Implantable cardioverter-defibrillators (ICD) have been shown to reduce mortality in patients with heart failure, but the benefit appears to be uneven in this population. We reviewed the evidence showing the benefit of ICD therapy in heart failure patients, the main issues arising from these studies, and the possible answers for a better risk stratification. In addition, we showed that multimodality imaging could improve patient selection for the implantation of ICDs, in both primary and secondary prevention, beyond the selection using only the left ventricular ejection fraction, by concentrating on arrhythmic substrate.
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Velcea et al. (2022) conducted a review in Heart failure. Multimodality imaging vs. Left ventricular ejection fraction only was evaluated. Multimodality imaging could improve patient selection for implantable cardioverter-defibrillators in heart failure beyond left ventricular ejection fraction by concentrating on arrhythmic substrate.
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