January 1, 2003Pacing and Clinical Electrophysiology
Comparison of the Cardiopulmonary Response to Exercise in Recipients of Dual Sensor DDDR Pacemakers Versus a Healthy Control Group
Key result
Patients with dual sensor DDDR pacemakers achieved similar peak VO2 and VE compared to healthy controls during exercise testing, despite having significantly lower peak heart rates.
Why the study?
Does a dual sensor DDDR pacemaker provide a cardiopulmonary response to exercise comparable to healthy controls in patients with chronotropic insufficiency?
Population
25 subjects capable of treadmill exercise with normal resting cardiopulmonary function and no cardiac…
Comparison
Dual sensor DDDR pacemaker evaluated during two… vs Healthy age-matched control group evaluated…
Design
Cross-sectional, CAEP and Harbor tests performed in randomized order
Authors
Discussion
Loading...
Member takes
Implication
Supports DDDR adaptation during exercise in small cohort; leaves open larger trials before practice implications.
Study Design
Type
Observational (n=25)
Randomization
Randomized order of exercise tests
Structured PICO
Does a dual sensor DDDR pacemaker provide a cardiopulmonary response to exercise comparable to healthy controls in patients with chronotropic insufficiency?
P
Population
25 subjects, including 9 patients with dual sensor pacemakers for chronotropic insufficiency and 16 healthy controls, undergoing treadmill exercise testing.
E
Exposure
Dual sensor DDDR pacemaker evaluated during two treadmill exercise protocols (CAEP and Harbor tests).
C
Comparator
Healthy age-matched control group evaluated during the same exercise protocols.
O
Outcome
Cardiopulmonary response to exercise (including VO2, VE, heart rate, metabolic reserve slope, plasma lactate concentrations, and dyspnea/fatigue scores).surrogate
Main Result
p-value: p=NS
Dual sensor DDDR pacemakers provide a cardiorespiratory response (VO2 and VE) comparable to healthy subjects during exercise, despite a lower peak heart rate.
Cite This Study
Page et al. (2003) conducted an observational in Chronotropic insufficiency (n=25). Dual sensor DDDR pacemaker vs. Healthy control group was evaluated on VO2 and VE at peak exercise (p=NS). Patients with dual sensor DDDR pacemakers achieved similar peak VO2 and VE compared to healthy controls during exercise testing, despite having significantly lower peak heart rates.