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July 15, 2026Expert Opinion on Drug Delivery

Bioinspired synthetic strategies for enhanced cell membrane interactions for targeted delivery of biomacromolecules

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Authors

NHNicole HenryAKApanpreet KaurRCRongjun Chen

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Overview

Review explores synthetic bioinspired systems for biomacromolecule delivery, suggesting new targeting methods.

Key Points

  • This review aims to explore innovative bioinspired delivery systems for biomacromolecules, focusing on overcoming delivery challenges.
  • Examined lipid- and polymer-based delivery systems for proteins and nucleic acids.
  • Classified virus-mimicking systems into structural and functional mimicry.
  • Discussed receptor-mediated transport and membrane penetration strategies.
  • Identified various systems enhancing cellular uptake and trafficking of biomacromolecules.
  • Highlighted the potential of multifunctional nanoparticles for precision delivery.
  • Emphasized the role of computational design and machine learning in optimizing delivery strategies.

Cite This Study

Henry et al. (2026) studied this question.

synapsesocial.com/papers/6a57226888b21df87547f730https://doi.org/10.1080/17425247.2026.2702442
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bioinspired nanocarriers for advanced drug delivery2025
  2. 2Bioinspired cellular membrane vesicles derived from bacterial and erythrocyte ghosts: Development and applications as a smart drug delivery system2024 · 4 citations
  3. 3Progress in non-endocytic dependent transmembrane delivery of biological macromolecules2026
  4. 4Advanced biomimetic nanomedicines for cell-based therapeutics: prospects and challenges2026 · 2 citations
  5. 5Biomimetic liposomes in drug delivery: from design mechanisms to applications2025