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July 15, 2026CureusOpen Access

Clinical Predictors and Outcomes of Post-transplantation Diabetes Mellitus in an Indian Kidney Transplant Cohort: The Predictive Value of Early Postoperative Hyperglycaemia

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Authors

PKPranjal KashivAPAmit S PasariMBManish Balwani

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Overview

Retrospective cohort study identifies early postoperative hyperglycaemia as a risk factor for diabetes in kidney transplant recipients, suggesting proactive management.

Key Points

  • This study aims to investigate the predictors and outcomes of post-transplantation diabetes mellitus (PTDM) in an Indian kidney transplant cohort.
  • Retrospective cohort study of 40 adult recipients of a first kidney transplant without pre-existing diabetes
  • Utilized tacrolimus-, corticosteroid-, and mycophenolate-based immunosuppression
  • Analyzed inpatient glucose trends, triglycerides, BMI, and used statistical tests to compare variables.
  • Cumulative incidence of PTDM was 20% (8/40), associated with older age (p < 0.001) and higher BMI (p < 0.001).
  • Postoperative hyperglycaemia occurred in 25% (10/40) and strongly correlated with PTDM (p = 0.001).
  • Of PTDM cases, 62.5% had persistent disease, diagnosed within four months post-transplant.

Cite This Study

Kashiv et al. (2026) studied this question.

synapsesocial.com/papers/6a57226888b21df87547f76bhttps://doi.org/10.7759/cureus.112534
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical profile and graft outcomes of post-transplant diabetes mellitus in renal transplant recipients: a retrospective study from a tertiary care center in South India2026
  2. 2Post-transplant diabetes mellitus in kidney transplant recipients: A prospective cohort study of risk factors and clinical outcomes2025 · 1 citations
  3. 3Beta Cell Dysfunction and Insulin Resistance in Posttransplant Diabetes Mellitus2026
  4. 4Post-Transplant Diabetes Mellitus in Kidney-Transplanted Patients: Related Factors and Impact on Long-Term Outcome2024 · 7 citations
  5. 5OC22 - Post-transplant glucose surge: identifying early metabolic risk in non-diabetic renal recipients2025