Key result
Among asymptomatic patients with abdominal aortic aneurysm, significant coronary artery disease was observed in 61%, with 31% fulfilling indications for coronary revascularization.
Why the study?
What is the prevalence and severity of asymptomatic coronary and carotid artery disease in patients with abdominal aortic aneurysm?
Cross-Sectional (n=100)
What is the prevalence and severity of asymptomatic coronary and carotid artery disease in patients with abdominal aortic aneurysm?
Severe asymptomatic coronary artery disease is highly prevalent in patients with abdominal aortic aneurysm, with nearly a third meeting criteria for coronary revascularization.
May warrant CAD screening in asymptomatic AAA; hypothesis-generating for revascularization benefit, needing prospective trials.
We evaluated the prevalence and severity of occult coronary artery disease (CAD) and cerebrovascular disease (CeVD) in patients with abdominal aortic aneurysm (AAA). We studied 100 consecutive patients with no history of CAD, normal electrocardiogram, normal systolic function, and no angina or dyspnea. All patients underwent carotid Doppler study and invasive coronary angiography. Significant CAD was observed in 61% of patients. In all, 51% of patients with significant CAD showed either left main (n = 7), 3-vessel (n = 17), or proximal left anterior descending (n = 7) CAD, corresponding to 31% of the total cohort. Cerebrovascular disease was detected in 53% of patients, and in 38% of them was significant (peak systolic flow velocity ≥125 <230 cm/s). In 36% of patients with CeVD either left main (n = 5), 3-vessel (n = 11), or proximal left anterior descending (n = 3) CAD was observed. Severe asymptomatic CAD is prevalent in AAA, and 31% of patients fulfill indications for coronary revascularization.
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Marsico et al. (2014) conducted a cross-sectional in Abdominal aortic aneurysm (n=100). Abdominal aortic aneurysm was evaluated on Prevalence of significant coronary artery disease. Among asymptomatic patients with abdominal aortic aneurysm, significant coronary artery disease was observed in 61%, with 31% fulfilling indications for coronary revascularization.
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