Key result
Post-operative troponin I elevation was independently associated with an increased long-term risk of death or acute myocardial infarction (adjusted HR 4.73; 95% CI 2.92-7.65; P<0.0001).
Why the study?
Does pre-operative ACC/AHA risk stratification and post-operative troponin I elevation predict death or myocardial infarction in patients undergoing elective major vascular surgery?
Population
391 consecutive patients undergoing elective major vascular surgery, prospectively stratified according to…
Comparison
Pre-operative stratification into three risk… vs Patients with minor or no clinical risk…
Design
Cohort
Follow-up
18 months
Authors
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May support troponin monitoring after vascular surgery; hypothesis-generating for intervention trials.
Cohort (n=391)
Does pre-operative ACC/AHA risk stratification and post-operative troponin I elevation predict death or myocardial infarction in patients undergoing elective major vascular surgery?
Hazard Ratio: 4.73 (95% CI 2.92–7.65)
p-value: p=<0.0001
Post-operative troponin I elevation and pre-operative ACC/AHA clinical risk predictors strongly and independently predict early and long-term death or MI in patients undergoing elective major vascular surgery.
Bursi et al. (2005) conducted a cohort in elective major vascular surgery (n=391). Post-operative troponin I (cTnI) elevation vs. No cTnI elevation was evaluated on death or acute myocardial infarction (MI) (HR 4.73, 95% CI 2.92-7.65, p=<0.0001). Post-operative troponin I elevation was independently associated with an increased long-term risk of death or acute myocardial infarction (adjusted HR 4.73; 95% CI 2.92-7.65; P<0.0001).
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